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Research Interests: Professor Bortz's research lies at the intersection of applied mathematics and statistics and is motivated by questions of biological and medical significance. Currently active and funded research includes: The application of model selection to post-therapy HIV infection dynamics and the development of general nonlinear model distinguishability and simulation accuracy criteria; The analytical and numerical study of fragmentation and aggregation properties of flocculating bacterial communities and their implications for optimum experimental design and clinical treatment of blood-borne infections; the development of an accurate and rheologically valid numerical scheme to simulate the fracture and separation (under flow) of a biofilm composed of bacterially-secreted visco-elastic polymer brushes; The creation of a hierarchical systems biology model of the alternative complement pathway for in silico study of the pathway's role in sepsis; the analysis of constraint-based metabolic flux models of green algae (C. reinhardtii) with the goal of improving its bio-hydrogen production efficiency; A Bayesian and Inverse Problems approach to identify optimal gridpoint locations for solving Boundary Value Problem/Partial Differential Equations. MathBio Group Page
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David Bortz North Carolina State University Office: ECOT 234 Phone: (303) 492-7569 Email Website
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Research Interests: Probability Theory Discrete Probability Percolation and Random Graphs Patterns in Random Strings Random Walks on Random Environments Graphical Models Math Biology
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Manuel Lladser Ohio State University-Columbus Office: ECOT 232 Phone: (303) 492-0694 Email Website
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Research Interests: Nonlinear Dynamics Dynamics on Complex Networks Structure of Networks Cardiac Dynamics Synchronization
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Juan Restrepo University of Maryland Office: ECOT 241 Phone: (303) 735-5640 Email Website
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